8-[(4-Amino-1-methylbutyl)amino]-2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinoline

Molecular Formula	C24H28F3N3O3
Molar Mass	463.49
Density	1.237±0.06 g/cm3(Predicted)
Melting Point	60 - 63°C
Boling Point	565.6±50.0 °C(Predicted)
Solubility	DMSO (Slightly), Methanol (Slightly)
Appearance	Solid
Color	Dark Orange to Very Dark Orange
pKa	10.36±0.10(Predicted)
Storage Condition	4°C
In vivo study	Tafenoquine exhibits no anti-malarial activity in CYP 2D knock-out mice when dosed at their ED 100 values (3 mg/kg) established in WT mice. Tafenoquine anti-malarial activity is partially restored in humanized/CYP 2D6 knock-in mice when tested at two times its ED 100 (6 mg/kg).

Product Name: Tafenoquine Request for quotation
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CAS: 106635-80-7
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Product Name: Tafenoquine Request for quotation
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052

Wechat: 15671228036

Product Name: Tafenoquine Visit Supplier Webpage Request for quotation
CAS: 106635-80-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

View History

Name	Tafenoquine
Synonyms	Krintafe KRINTAFE WR238605 SB252263 WR 238605 SB-252263 WR-238605 SB 252263 TAFENOQUINE Tafenoquine TAFENOQUINE SB252263-AAB SB 252263-AAB WR-238605, WR 238605, WR238605, SB-252263-AAB 4-[5-[3-(Trifluoromethyl)phenoxy]-2,6-dimethoxy-4-methyl-8-quinolinylamino]-1-pentanamine N4-(2,6-diMethoxy-4-Methyl-5-(3-(trifluoroMethyl)phenoxy)quinolin-8-yl)pentane-1,4-diaMine N4-{2,6-Dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]-8-quinolinyl}-1,4-pentanediamine 8-[(4-Amino-1-methylbutyl)amino]-2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinoline
CAS	106635-80-7

8-[(4-Amino-1-methylbutyl)amino]-2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinoline Request for Quotation